One hour ago
- copy link
Scientists in Japan have prepared a cholera vaccine from rice. The first human trial of the vaccine has been successful. Scientists from Tokyo and Chiba University, who developed the vaccine, claim that it has shown no side effects during the trial and has shown a better immune response. This vaccine has been named Muco-Rice-CTB. The results of the first phase of the trial have been published in the Lancet Microbe journal.
Understand the specialty of vaccine in 3 points
This is how the vaccine works
Researcher Hiroshi Kiyono of the University of Tokyo says, during the trial, patients were given low (3mg), medium (6mg) and high (18mg) doses of the vaccine. But the highest response was seen in high doses. IgA and IgG antibodies were found in patients in the second and fourth months after giving the vaccine. IgA and IgG antibodies are special proteins that the immune system releases. This protein fights infection with cholera toxin-B.
Vaccine can be given with saline water
To prepare the vaccine, scientists planted small grain plants of genetically modified rice in indoor farms. The rice was plucked after the crop was ready. It was ground very finely and kept in aluminum packets for storage. During vaccination, this powder was mixed with 1/3 cup of saline water and given to the patient. Scientists say, it can also be given to the patient with plain water.
Know the disease now